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BLU-451 (EGFR exon 20 insertion inhibitor)
Blueprint Medicines
Dec 19, 2023
4
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KT-474 (IRAK4 degrader) ✔️
Kymera Therapeutics
Aug 7, 2023
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KT-413 (IRAKIMiD degrader)
Kymera Therapeutics
Jul 27, 2023
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VX-548 (NaV 1.8 inhibitor) ✔️
Feb 13, 2023
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VX-548 (NaV 1.8 inhibitor) ✔️
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DFV890 (NLRP3 inhibitor)
Mar 13, 2023
2
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STC-15 (METTL3 inhibitor) ✔️
Jun 26, 2023
1
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IDE397 (MAT2A inhibitor)
May 3, 2023
2
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IDE397 (MAT2A inhibitor)
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KIN-3248 (pan-FGFR inhibitor) ✔️
Jul 17, 2023
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KIN-3248 (pan-FGFR inhibitor) ✔️
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MK-0616 (PCSK9 inhibitor) ✔️
Mar 22, 2023
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KIN-3248 (pan-FGFR inhibitor) ✔️
Kinnate Biopharma
Jul 17, 2023
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STC-15 (METTL3 inhibitor) ✔️
STORM Therapeutics
Jun 26, 2023
1
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2
ATI-2231 (MK2 inhibitor)
Aclaris Therapetuics
May 29, 2023
2
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IDE397 (MAT2A inhibitor)
Ideaya Biosciences
May 3, 2023
2
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SAGE-324 (GABA-A receptor positive allosteric modulator)
Sage Therapeutics/Biogen
Apr 17, 2023
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SAGE-324 (GABA-A receptor positive allosteric modulator)
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MK-0616 (PCSK9 inhibitor) ✔️
Merck & Co.
Mar 22, 2023
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BI 1015550 (PDE4 inhibitor) ✔️
Boehringer Ingelheim
Mar 20, 2023
2
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BI 1015550 (PDE4 inhibitor) ✔️
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